HitPredict

Interactor 1: TRAF2 (P39429)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2)
Gene: TRAF2

Interactor 2: CD27 (P41272)
CD27 antigen (CD27L receptor) (T-cell activation antigen CD27) (Tumor necrosis factor receptor superfamily member 7) (CD antigen CD27)
Gene: CD27

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	20974987, 9692890
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043066 - negative regulation of apoptotic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 501 Mm			1 250
+	Hs
		645795 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		CD27_HUMAN (1-250): 4.26e-71: 220: 64.62
+	Mm
		648951 TRAF2_MOUSE (1-501): 1.58e-154: 451: 100.00		TNR5_MOUSE (6-246): 1e-53: 176: 18.39
+	Hs
		639576 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR5_HUMAN (6-246): 8.35e-54: 176: 18.53
+	Mm
		192583 TRAF2_MOUSE (1-501): 1.58e-154: 451: 100.00		TNR11_MOUSE (4-218): 1.69e-45: 162: 14.64
+	Hs
		584390 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR1A_HUMAN (11-250): 7.39e-47: 163: 19.84
+	Mm
		761824 TRAF2_MOUSE (1-501): 1.58e-154: 451: 100.00		TNR14_MOUSE (7-208): 5.07e-39: 138: 18.35
+	Hs
		738659 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR3_HUMAN (4-196): 7.02e-40: 144: 17.49
+	Hs
		591317 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR1B_HUMAN (13-178): 2.26e-35: 132: 20.00
+	Hs
		1020937 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR27_HUMAN (26-246): 9.21e-36: 130: 18.18
+	Mm
		761805 TRAF2_MOUSE (1-501): 1.58e-154: 451: 100.00		TNR3_MOUSE (30-179): 1.2e-27: 111: 18.94
+	Hs
		1020846 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR14_HUMAN (6-235): 2.04e-31: 118: 20.90
+	Hs
		154352 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TR10B_HUMAN (42-185): 2.11e-28: 113: 17.24
+	Mm
		761804 TRAF2_MOUSE (1-501): 1.58e-154: 451: 100.00		TNR4_MOUSE (30-184): 2.11e-24: 99.9: 23.67
+	Hs
		121479 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TR10A_HUMAN (16-151): 1.18e-26: 109: 16.06
+	Mm
		626852 TRAF2_MOUSE (1-501): 1.58e-154: 451: 100.00		TNR1A_MOUSE (11-153): 5.48e-22: 95.6: 18.85
+	Hs
		1020849 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR25_HUMAN (19-244): 2.1e-23: 99.5: 17.65
+	Hs
		796823 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR4_HUMAN (9-184): 1.94e-23: 97.6: 21.28
+	Hs
		436618 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR16_HUMAN (23-164): 2.45e-17: 82.5: 17.33
+	Mm
		591445 TRAF2_MOUSE (1-501): 1.58e-154: 451: 100.00		TNR9_MOUSE (37-189): 3.33e-11: 63.3: 18.99
+	Hs
		989742 TRAF2_HUMAN (1-501): 7.77e-150: 439: 86.83		TNR9_HUMAN (40-167): 6.03e-10: 59.8: 21.54