HitPredict

Interactor 1: TRAF2 (P39429)
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2)
Gene: TRAF2

Interactor 2: BIRC2 (Q62210)
Baculoviral IAP repeat-containing protein 2 (EC 2.3.2.27) (Cellular inhibitor of apoptosis 1) (C-IAP1) (Inhibitor of apoptosis protein 2) (mIAP2) (RING-type E3 ubiquitin transferase BIRC2)
Gene: BIRC2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.726

The method score is based on:

Property Details
Experiments 21765415, 15102471
Identification Methods anti bait coimmunoprecipitation, two hybrid
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BIR~TRAF_BIRC3_bd
Common GO terms GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0008270 - zinc ion binding
GO:0009898 - cytoplasmic side of plasma membrane
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 501
Mm

1 612
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024