Interactor 1: ZO1 (P39447)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: Tjp1

Interactor 2: ACTN4 (P57780)
Alpha-actinin-4 (Non-muscle alpha-actinin 4)
Gene: ACTN4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 16944923
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Spectrin~ZU5
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0030054 - cell junction
and 1 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1745
Mm

1 912
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Ce
+ Ce
+ Ce
+ Mm
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024