HitPredict

Interactor 1: DHH1 (P39517)
ATP-dependent RNA helicase DHH1 (EC 3.6.4.13) (DExD/H-box helicase 1)
Gene: DHH1

Interactor 2: EIF2A (P53235)
Eukaryotic translation initiation factor 2A (eIF-2A)
Gene: YGR054W

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.614

Property	Details
Experiments	26392412, 18467557
Identification Methods	affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 506 Sc			1 642
+	Hs
		640385 DDX6_HUMAN (3-421): 1.32e-156: 456: 66.43		EIF3B_HUMAN (5-505): 9.99e-161: 483: 16.50
+	Hs
		133945 DDX3X_HUMAN (2-444): 3.06e-129: 392: 27.08		EIF3B_HUMAN (5-505): 9.99e-161: 483: 16.50
+	Sc
		410124 DHH1_YEAST (17-506): 2.67e-149: 438: 100.00		EIF3B_YEAST (4-506): 2.91e-126: 392: 15.06
+	Hs
		879191 IF4A1_HUMAN (46-413): 5.64e-89: 280: 44.47		EIF3B_HUMAN (5-505): 9.99e-161: 483: 16.50
+	Mm
		892957 IF4A1_MOUSE (46-413): 5.64e-89: 280: 44.47		EIF3B_MOUSE (5-505): 2.71e-159: 479: 16.50
+	Dm
		972127 IF4A_DROME (46-413): 3.47e-92: 288: 44.87		EIF3B_DROME (13-503): 2.13e-144: 437: 15.98