HitPredict

Interactor 1: AN32A (P39687)
Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (pp32) (Leucine-rich acidic nuclear protein) (LANP) (Mapmodulin) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Putative HLA-DR-associated protein I) (PHAPI)
Gene: ANP32A

Interactor 2: IMA5 (P52294)
Importin subunit alpha-5 (Karyopherin subunit alpha-1) (Nucleoprotein interactor 1) (NPI-1) (RAG cohort protein 2) (SRP1-beta) [Cleaved into: Importin subunit alpha-5, N-terminally processed]
Gene: KPNA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	35271311, 16713569
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0042981 - regulation of apoptotic process
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 249 Hs			1 538
+	Hs
		238714 AN32B_HUMAN (1-248): 1.23e-41: 144: 66.53		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		238731 AN32E_HUMAN (1-153): 2.15e-38: 136: 70.59		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		853670 AN32B_HUMAN (1-248): 1.23e-41: 144: 66.53		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		168660 AN32B_HUMAN (1-248): 1.23e-41: 144: 66.53		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Hs
		853697 AN32E_HUMAN (1-153): 2.15e-38: 136: 70.59		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		238637 AN32A_HUMAN (1-239): 7.48e-33: 121: 100.00		IMA7_HUMAN (1-538): 6.51e-160: 467: 80.48
+	Hs
		168666 AN32E_HUMAN (1-153): 2.15e-38: 136: 70.59		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Hs
		853620 Q5TB19_HUMAN (1-109): 1.34e-32: 117: 71.56		IMA5_HUMAN (1-538): 9.01e-156: 457: 100.00
+	Hs
		168621 AN32A_HUMAN (1-239): 7.48e-33: 121: 100.00		IMA6_HUMAN (1-538): 1.39e-152: 449: 79.59
+	Dm
		853810 Q9VZI4_DROME (41-174): 6.73e-30: 117: 25.74		IMA_DROME (3-538): 3.76e-121: 367: 43.60
+	Dm
		853785 Q8IRC2_DROME (44-174): 7.26e-20: 89: 26.32		IMA_DROME (3-538): 3.76e-121: 367: 43.60