Interactor 1: FYN (P39688)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)
Gene: FYN

Interactor 2: PTN5 (P54830)
Tyrosine-protein phosphatase non-receptor type 5 (EC 3.1.3.48) (Neural-specific protein-tyrosine phosphatase) (Striatum-enriched protein-tyrosine phosphatase) (STEP)
Gene: Ptpn5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 27457929, 25951993
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Y_phosphatase, SH2~Y_phosphatase
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0010976 - positive regulation of neuron projection development
GO:0043204 - perikaryon
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 537
Mm

1 541
+ Hs
+ Rn
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Rn
+ Hs
+ Rn
+ Hs
+ Rn
+ Hs
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024