Interactor 1: FYN (P39688)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)
Gene: FYN

Interactor 2: EPHA4 (Q03137)
Ephrin type-A receptor 4 (EC 2.7.10.1) (Tyrosine-protein kinase receptor MPK-3) (Tyrosine-protein kinase receptor SEK-1)
Gene: EPHA4

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 8622893
Identification Methods surface plasmon resonance, biochemical
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EphA2_TM~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, SH2~fn3, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0014069 - postsynaptic density
GO:0018108 - peptidyl-tyrosine phosphorylation
and 7 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 537
Mm

1 986
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Last updated: 15 Jul 2024