Interactor 1: FYN (P39688)
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)
Gene: FYN

Interactor 2: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 7499280
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1, SH2~SH2, SH2~SH3_1, SH3_1~SH3_1
Common GO terms GO:0005634 - nucleus
GO:0005768 - endosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0019899 - enzyme binding
and 3 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 537
Mm

1 217
+ Hs
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+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm
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+ Hs
+ Hs
+ Hs
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+ Rn
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+ Rn
+ Gg
+ Mm

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Last updated: 15 Jul 2024