HitPredict

Interactor 1: CDN1A (P39689)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein) (p21)
Gene: Cdkn1a

Interactor 2: CDK2 (P97377)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2)
Gene: CDK2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.957

The method score is based on:

Property Details
Experiments 15107404, 18729080, 18356301, 15155733, 9488036, 12970760, 10348346, 16982699
Identification Methods affinity chromatography technology, coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Pkinase
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 159
Mm

1 346
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+ Rn
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+ Xl
+ Xl
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+ Xl
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024