HitPredict

Interactor 1: VPS8 (P39702)
Vacuolar protein sorting-associated protein 8 (Vacuolar protein-targeting protein 8)
Gene: VPS8

Interactor 2: VAM6 (Q07468)
Vacuolar morphogenesis protein 6 (Vacuolar protein sorting-associated protein 39)
Gene: VAM6

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.677

Property	Details
Experiments	25026036, 36076954, 21325627, 37968396
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030897 - HOPS complex GO:0034058 - endosomal vesicle fusion GO:0099022 - vesicle tethering
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1274 Sc			1 1049
+	Sc
		653809 VPS8_YEAST (1-1274): 0: 1966: 100.00		PEP3_YEAST (628-1037): 3.82e-56: 212: 13.40
+	Sc
		619697 VPS8_YEAST (1-1274): 0: 1966: 100.00		VPS3_YEAST (544-967): 2.45e-51: 198: 14.32
+	Sc
		758407 VPS8_YEAST (1-1274): 0: 1966: 100.00		VPS41_YEAST (643-984): 1.07e-37: 155: 12.61
+	Hs
		1232463 VPS8_HUMAN (521-1269): 0: 651: 19.17		TGFA1_HUMAN (575-1029): 6.16e-81: 284: 19.19
+	Hs
		1232471 VPS8_HUMAN (521-1269): 0: 651: 19.17		VPS11_HUMAN (605-1031): 4.31e-77: 274: 14.22
+	Hs
		1232473 VPS8_HUMAN (521-1269): 0: 651: 19.17		VPS18_HUMAN (547-1017): 2.63e-68: 249: 13.35
+	Dm
		1097263 VPS8_DROME (514-1268): 0: 577: 21.04		VPS18_DROME (574-1042): 3.96e-64: 237: 14.68