HitPredict

Interactor 1: RV167 (P39743)
Reduced viability upon starvation protein 167
Gene: RVS167

Interactor 2: LAS17 (Q12446)
Proline-rich protein LAS17
Gene: LAS17

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.97	0.60	0.765

Property	Details
Experiments	11489916, 10688190, 10992286, 10512884, 11743162, 11283351, 11805837, 26312755, 10388809, 14737190, 15561700, 19841731, 19272406, 12857883, 18719252, 21035341, 23267104
Identification Methods	two hybrid, coimmunoprecipitation, two hybrid pooling approach, anti tag coimmunoprecipitation, unspecified method, affinity chromatography technology, far western blotting, phage display, miniaturized immunoprecipitation, peptide array and 1 others more... surface plasmon resonance
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0030479 - actin cortical patch GO:0043332 - mating projection tip GO:0051666 - actin cortical patch localization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Sc			1 633
+	Mm
		1141101 SRC8_MOUSE (15-481): 2.99e-52: 186: 13.89		WASL_MOUSE (3-154): 6.45e-45: 169: 28.95
+	Sc
		979583 MYO5_YEAST (6-479): 1.82e-43: 166: 11.27		LAS17_YEAST (1-633): 8.22e-51: 188: 100.00
+	Sc
		629680 RV161_YEAST (1-270): 6.55e-47: 165: 24.35		LAS17_YEAST (1-633): 8.22e-51: 188: 100.00
+	Mm
		139043 BIN1_MOUSE (3-481): 3.2e-49: 179: 13.71		WASL_MOUSE (3-154): 6.45e-45: 169: 28.95
+	Sp
		193724 HOB1_SCHPO (1-479): 2.24e-74: 243: 43.01		WSP1_SCHPO (4-416): 3.99e-22: 102: 22.03
+	Hs
		126934 SRC8_HUMAN (15-481): 1.07e-49: 180: 15.01		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Hs
		126878 BIN1_HUMAN (3-481): 3.89e-49: 179: 12.67		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Sc
		730603 MYO3_YEAST (6-482): 7.31e-39: 153: 9.82		LAS17_YEAST (1-633): 8.22e-51: 188: 100.00
+	Hs
		126969 PACN2_HUMAN (5-481): 2.54e-49: 177: 15.28		WASL_HUMAN (3-154): 1.13e-42: 163: 28.29
+	Rn
		139963 SRC8_RAT (7-481): 8.75e-46: 168: 13.87		WASL_RAT (3-154): 1.43e-45: 170: 28.95
+	Dm
		1361424 Q9VDI1_DROME (5-478): 3e-41: 155: 16.12		Q9VAT0_DROME (3-215): 8.21e-40: 154: 18.18
+	Rn
		139991 BIN1_RAT (3-481): 5.26e-49: 178: 13.71		SYNJ1_RAT (131-630): 3.06e-28: 123: 13.09
+	Hs
		790671 SRC8_HUMAN (15-481): 1.07e-49: 180: 15.01		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Hs
		790694 PACN2_HUMAN (5-481): 2.54e-49: 177: 15.28		WASP_HUMAN (3-448): 2.5e-27: 117: 16.52
+	Hs
		203262 PACN2_HUMAN (5-481): 2.54e-49: 177: 15.28		SYNJ1_HUMAN (89-538): 6.62e-22: 103: 12.06
+	Hs
		1052365 SRC8_HUMAN (15-481): 1.07e-49: 180: 15.01		CABIN_HUMAN (128-579): 2.58e-19: 95.2: 17.99
+	Hs
		203224 MYO1E_HUMAN (5-480): 8.88e-45: 170: 14.14		SYNJ1_HUMAN (89-538): 6.62e-22: 103: 12.06
+	Sp
		193734 MYO1_SCHPO (6-481): 6.69e-44: 167: 12.93		WSP1_SCHPO (4-416): 3.99e-22: 102: 22.03
+	Sp
		194039 MYO1_SCHPO (6-481): 6.69e-44: 167: 12.93		YFHH_SCHPO (80-563): 7.3e-14: 77.5: 11.57
+	Ce
		70017 SH3GH_CAEEL (75-479): 1.98e-46: 167: 18.43		G5EBN5_CAEEL (180-491): 1.73e-09: 63.2: 14.10