HitPredict

Interactor 1: PHP (P39769)
Polyhomeotic-proximal chromatin protein
Gene: ph-p

Interactor 2: Q9VV77 (Q9VV77)
Lethal (3) 73Ah, isoform A (Lethal (3) 73Ah, isoform B) (RE11339p)
Gene: l(3)73Ah

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	14605208, 36070387
Identification Methods	two hybrid, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0008270 - zinc ion binding GO:0035102 - PRC1 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1589 Dm			1 222
+	Dm
		728795 PHP_DROME (1-1589): 3.16e-132: 451: 100.00		PSC_DROME (2-218): 1.16e-48: 172: 34.69
+	Dm
		627164 PHP_DROME (1-1589): 3.16e-132: 451: 100.00		SUZ2_DROME (7-218): 1.08e-42: 155: 24.55
+	Dm
		764510 PHP_DROME (1-1589): 3.16e-132: 451: 100.00		RING1_DROME (2-124): 8.01e-29: 113: 21.77
+	Dm
		1374688 Q9W523_DROME (87-1585): 9.24e-78: 287: 83.73		Q9VV77_DROME (1-222): 3.14e-65: 203: 100.00
+	Dm
		1341979 Q9NF31_DROME (244-1585): 1.24e-68: 257: 87.22		Q9VV77_DROME (1-222): 3.14e-65: 203: 100.00
+	Dm
		728804 Q9NF31_DROME (244-1585): 1.24e-68: 257: 87.22		PSC_DROME (2-218): 1.16e-48: 172: 34.69
+	Dm
		627168 Q9NF31_DROME (244-1585): 1.24e-68: 257: 87.22		SUZ2_DROME (7-218): 1.08e-42: 155: 24.55
+	Hs
		1108515 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		PCGF3_HUMAN (1-222): 1.25e-61: 194: 54.55
+	Hs
		1220909 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		R4GMX3_HUMAN (2-219): 3e-57: 189: 36.91
+	Hs
		717999 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		BMI1_HUMAN (2-219): 9.77e-59: 189: 36.91
+	Dm
		1341975 Q9NF31_DROME (244-1585): 1.24e-68: 257: 87.22		RING1_DROME (2-124): 8.01e-29: 113: 21.77
+	Hs
		718408 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		PCGF2_HUMAN (2-219): 1.09e-55: 182: 35.17
+	Hs
		718098 SCMH1_HUMAN (1148-1576): 1.88e-42: 168: 17.83		BMI1_HUMAN (2-219): 9.77e-59: 189: 36.91
+	Hs
		1220881 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		PCGF1_HUMAN (2-219): 3.55e-53: 173: 39.82
+	Hs
		718418 SCMH1_HUMAN (1148-1576): 1.88e-42: 168: 17.83		PCGF2_HUMAN (2-219): 1.09e-55: 182: 35.17
+	Hs
		1197568 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		PCGF5_HUMAN (2-222): 1.99e-47: 158: 37.01
+	Hs
		1220886 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		PCGF6_HUMAN (2-216): 2.25e-44: 153: 38.12
+	Hs
		1220877 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		RING2_HUMAN (1-124): 1.78e-31: 119: 21.60
+	Hs
		987988 PHC2_HUMAN (734-1577): 1.55e-46: 183: 20.27		RING1_HUMAN (2-124): 2.4e-29: 114: 22.58
+	Mm
		1225135 SCMH1_MOUSE (1140-1577): 2.01e-43: 172: 17.48		RING2_MOUSE (1-124): 1.56e-31: 119: 21.60