HitPredict

Interactor 1: CUX1 (P39880)
Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (CDP/Cux p200) (Homeobox protein cux-1) [Cleaved into: CDP/Cux p110]
Gene: CUX1

Interactor 2: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11584018
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1505 Hs			1 346
+	Hs
		414798 CUX1_HUMAN (1-1505): 2.44e-132: 449: 100.00		CDK1_HUMAN (9-298): 6.62e-135: 387: 43.00
+	Hs
		686552 OTX2_HUMAN (1212-1505): 1.83e-58: 205: 14.33		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		960127 LHX3_HUMAN (1231-1480): 1.49e-48: 180: 20.08		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		502908 MYH3_HUMAN (100-1020): 1.76e-31: 137: 9.08		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		522542 MYH1_HUMAN (100-1048): 3.46e-31: 136: 7.56		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		522604 MYH7_HUMAN (7-823): 6.78e-30: 132: 9.28		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		528401 MYH8_HUMAN (4-645): 1.05e-23: 111: 10.98		CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85
+	Hs
		960128 MYH2_HUMAN (219-993): 2.61e-28: 126: 9.06		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		528405 MYH8_HUMAN (4-645): 1.05e-23: 111: 10.98		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		625176 MYH9_HUMAN (384-1281): 7.42e-17: 89.4: 7.20		CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85
+	Hs
		625536 RAD50_HUMAN (9-422): 2.37e-16: 87.4: 17.20		CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85
+	Hs
		724717 MYH9_HUMAN (384-1281): 7.42e-17: 89.4: 7.20		CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00
+	Hs
		625177 MYH10_HUMAN (1-336): 1.78e-11: 71.7: 12.87		CDK2_HUMAN (9-307): 2.6e-150: 426: 43.85
+	Hs
		725114 MYH10_HUMAN (1-336): 1.78e-11: 71.7: 12.87		CDK7_HUMAN (1-346): 2.36e-147: 420: 100.00
+	Hs
		528368 MYH6_HUMAN (2-389): 2.03e-13: 77.8: 10.80		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		960129 MYH13_HUMAN (1-398): 3.41e-10: 67.4: 11.36		CDK3_HUMAN (9-307): 7.94e-143: 407: 44.85
+	Hs
		1224563 RAD50_HUMAN (9-422): 2.37e-16: 87.4: 17.20		CDK20_HUMAN (11-310): 1.24e-77: 243: 43.28