Interactor 1: IL13 (P35225)
Interleukin-13 (IL-13)
Gene: IL13
Interactor 2: I13R2 (Q14627)
Interleukin-13 receptor subunit alpha-2 (IL-13 receptor subunit alpha-2) (IL-13R subunit alpha-2) (IL-13R-alpha-2) (IL-13RA2) (Interleukin-13-binding protein) (CD antigen CD213a2)
Gene: IL13RA2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.955 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22952195, 11313257, 8663118, 20223216, 27629921, 23972995 |
| Identification Methods | pull down, biochemical, x-ray crystallography, isothermal titration calorimetry, molecular sieving, surface plasmon resonance, protein cross-linking with a bifunctional reagent, saturation binding, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IL13~IL6Ra-bind |
| Common GO terms | GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0009897 - external side of plasma membrane GO:0035772 - interleukin-13-mediated signaling pathway |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
