HitPredict

Interactor 1: IF4F2 (P39936)
Eukaryotic initiation factor 4F subunit p130 (eIF-4F p130) (eIF4F p130) (Translation initiation factor 4(4)-F(6) subunit gamma(3) protein 2) (eIF4G2) (mRNA cap-binding protein complex subunit p130)
Gene: TIF4632

Interactor 2: YRA1 (Q12159)
RNA annealing protein YRA1
Gene: YRA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	15584090, 17922018, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 914 Sc			1 226
+	Sc
		376797 IF4F2_YEAST (1-914): 0: 614: 100.00		PABP_YEAST (58-163): 4.29e-13: 69.8: 18.69
+	Sc
		765101 IF4F1_YEAST (1-914): 1.37e-142: 449: 47.13		YRA1_YEAST (1-226): 7.45e-51: 166: 100.00
+	Sc
		376796 IF4F1_YEAST (1-914): 1.37e-142: 449: 47.13		PABP_YEAST (58-163): 4.29e-13: 69.8: 18.69
+	Hs
		979983 IF4G1_HUMAN (19-906): 2.59e-119: 399: 16.78		PDIP3_HUMAN (33-195): 3.43e-28: 111: 18.68
+	Hs
		979889 IF4G1_HUMAN (19-906): 2.59e-119: 399: 16.78		PABP4_HUMAN (70-162): 7.24e-17: 80.6: 20.21
+	Hs
		516476 IF4G1_HUMAN (19-906): 2.59e-119: 399: 16.78		PABP1_HUMAN (74-162): 4.86e-16: 78.3: 20.00
+	Hs
		198810 IF4G3_HUMAN (2-868): 6.9e-109: 370: 17.54		RFOX2_HUMAN (35-179): 1.17e-22: 96.5: 21.19
+	Hs
		203335 IF4G3_HUMAN (2-868): 6.9e-109: 370: 17.54		PABP1_HUMAN (74-162): 4.86e-16: 78.3: 20.00
+	Hs
		1154073 NIPBL_HUMAN (34-581): 6.8e-56: 213: 12.86		PDIP3_HUMAN (33-195): 3.43e-28: 111: 18.68
+	Pf
		1211776 Q8IIS9_PLAF7 (542-834): 1.06e-64: 240: 20.13		Q8I5H4_PLAF7 (66-171): 2.32e-13: 70.6: 14.95
+	Hs
		998855 EP300_HUMAN (8-465): 2.15e-38: 158: 10.92		THOC4_HUMAN (1-225): 3.86e-44: 150: 21.65
+	Mm
		665767 PAIP1_MOUSE (494-811): 8.43e-61: 214: 16.11		PABP1_MOUSE (74-162): 5.1e-16: 78.3: 20.00
+	Hs
		1119144 PAIP1_HUMAN (453-811): 8.3e-55: 199: 16.22		PAP1L_HUMAN (78-162): 2.09e-18: 85.2: 20.93
+	Hs
		1031455 PAIP1_HUMAN (453-811): 8.3e-55: 199: 16.22		PABP4_HUMAN (70-162): 7.24e-17: 80.6: 20.21
+	Hs
		516685 PAIP1_HUMAN (453-811): 8.3e-55: 199: 16.22		PABP1_HUMAN (74-162): 4.86e-16: 78.3: 20.00
+	Hs
		999062 EP300_HUMAN (8-465): 2.15e-38: 158: 10.92		PDIP3_HUMAN (33-195): 3.43e-28: 111: 18.68
+	Hs
		998651 EP300_HUMAN (8-465): 2.15e-38: 158: 10.92		PABP4_HUMAN (70-162): 7.24e-17: 80.6: 20.21
+	Hs
		516480 EP300_HUMAN (8-465): 2.15e-38: 158: 10.92		PABP1_HUMAN (74-162): 4.86e-16: 78.3: 20.00
+	Hs
		516595 KMT2C_HUMAN (9-529): 1.98e-11: 70.6: 8.05		PABP1_HUMAN (74-162): 4.86e-16: 78.3: 20.00