HitPredict

Interactor 1: GDI1 (P39958)
Rab GDP-dissociation inhibitor (Rab GDI) (Secretory pathway GDP dissociation inhibitor)
Gene: GDI1

Interactor 2: YPT32 (P51996)
GTP-binding protein YPT32/YPT11 (Rab GTPase YPT32)
Gene: YPT32

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

Property	Details
Experiments	11805837, 18467557, 37968396, 11785952, 22157956
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, protein complementation assay, two hybrid, dihydrofolate reductase reconstruction
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0015031 - protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 451 Sc			1 222
+	Sc
		750738 GDI1_YEAST (1-451): 0: 667: 100.00		YPT31_YEAST (1-222): 1.28e-87: 259: 80.72
+	Mm
		838709 GDIA_MOUSE (6-450): 0: 653: 54.04		RAB1A_MOUSE (1-222): 2.65e-87: 258: 41.44
+	Hs
		678344 GDIA_HUMAN (6-450): 0: 652: 53.81		RAB1A_HUMAN (1-222): 2.65e-87: 258: 41.44
+	Hs
		838625 GDIB_HUMAN (6-450): 0: 651: 54.04		RAB1A_HUMAN (1-222): 2.65e-87: 258: 41.44
+	Hs
		678341 GDIA_HUMAN (6-450): 0: 652: 53.81		RAB14_HUMAN (1-221): 9.78e-85: 252: 45.70
+	Hs
		678394 GDIA_HUMAN (6-450): 0: 652: 53.81		RAB1B_HUMAN (6-222): 3.78e-85: 252: 43.78
+	Hs
		678343 GDIA_HUMAN (6-450): 0: 652: 53.81		RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72
+	Hs
		678359 GDIA_HUMAN (6-450): 0: 652: 53.81		RB11B_HUMAN (4-222): 2.1e-84: 251: 58.90
+	Hs
		678377 GDIA_HUMAN (6-450): 0: 652: 53.81		RAB2B_HUMAN (10-222): 1.43e-84: 251: 39.25
+	Hs
		838621 GDIB_HUMAN (6-450): 0: 651: 54.04		RAB14_HUMAN (1-221): 9.78e-85: 252: 45.70
+	Hs
		838683 GDIB_HUMAN (6-450): 0: 651: 54.04		RAB1B_HUMAN (6-222): 3.78e-85: 252: 43.78
+	Hs
		838624 GDIB_HUMAN (6-450): 0: 651: 54.04		RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72
+	Hs
		838647 GDIB_HUMAN (6-450): 0: 651: 54.04		RB11B_HUMAN (4-222): 2.1e-84: 251: 58.90
+	Hs
		838669 GDIB_HUMAN (6-450): 0: 651: 54.04		RAB2B_HUMAN (10-222): 1.43e-84: 251: 39.25
+	Sp
		568530 GDI1_SCHPO (6-451): 0: 630: 61.44		YPT3_SCHPO (7-222): 1.68e-89: 264: 61.29
+	Dm
		185501 Q9VLB7_DROME (6-448): 0: 625: 53.38		O18332_DROME (1-222): 2.45e-83: 248: 40.99
+	Dm
		185708 Q9VLB7_DROME (6-448): 0: 625: 53.38		O18335_DROME (4-222): 3.93e-83: 247: 59.82
+	Hs
		838614 GDIB_HUMAN (6-450): 0: 651: 54.04		RAB25_HUMAN (9-202): 8.48e-69: 211: 54.64
+	Dm
		1197044 Q9VLB7_DROME (6-448): 0: 625: 53.38		Q86BK8_DROME (8-214): 5.1e-61: 192: 47.34
+	Dm
		185694 RABEP_DROME (6-435): 5.71e-139: 410: 24.14		O18335_DROME (4-222): 3.93e-83: 247: 59.82