HitPredict

Interactor 1: HSP7E (P39987)
Heat shock protein SSC3, mitochondrial (Extracellular mutant protein 10)
Gene: ECM10

Interactor 2: SKM1 (Q12469)
Serine/threonine-protein kinase SKM1 (EC 2.7.11.1) (Protein kinase 75490 D)
Gene: SKM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 644 Sc			1 655
+	Sc
		478483 HSP77_YEAST (14-631): 0: 969: 83.33		STE20_YEAST (123-653): 9.08e-123: 388: 32.53
+	Sc
		477838 HSP77_YEAST (14-631): 0: 969: 83.33		YPK1_YEAST (59-655): 3.09e-121: 377: 16.33
+	Hs
		504007 HSP7C_HUMAN (25-631): 0: 885: 47.42		PAK1_HUMAN (69-652): 1.55e-149: 446: 33.50
+	Hs
		564066 HSP76_HUMAN (26-629): 0: 876: 46.19		PAK1_HUMAN (69-652): 1.55e-149: 446: 33.50
+	Hs
		871551 HSP72_HUMAN (25-630): 0: 874: 47.34		PAK1_HUMAN (69-652): 1.55e-149: 446: 33.50
+	Hs
		871553 HSP72_HUMAN (25-630): 0: 874: 47.34		PAK2_HUMAN (120-652): 1.08e-142: 427: 35.84
+	Hs
		503528 HSP7C_HUMAN (25-631): 0: 885: 47.42		AKT1_HUMAN (245-654): 3.78e-123: 375: 19.81
+	Hs
		564016 HSP76_HUMAN (26-629): 0: 876: 46.19		AKT1_HUMAN (245-654): 3.78e-123: 375: 19.81
+	Hs
		713953 HS71L_HUMAN (25-641): 0: 886: 46.03		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		503996 HSP7C_HUMAN (25-631): 0: 885: 47.42		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		564065 HSP76_HUMAN (26-629): 0: 876: 46.19		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		871550 HSP72_HUMAN (25-630): 0: 874: 47.34		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		160349 HSP7C_HUMAN (25-631): 0: 885: 47.42		AURKA_HUMAN (279-644): 3.21e-105: 326: 23.86
+	Hs
		160460 HSP72_HUMAN (25-630): 0: 874: 47.34		AURKA_HUMAN (279-644): 3.21e-105: 326: 23.86
+	Hs
		681702 GRP75_HUMAN (4-630): 0: 768: 63.43		AKT1_HUMAN (245-654): 3.78e-123: 375: 19.81
+	Hs
		751605 GRP75_HUMAN (4-630): 0: 768: 63.43		STK4_HUMAN (331-654): 2e-116: 358: 32.41
+	Hs
		160419 GRP75_HUMAN (4-630): 0: 768: 63.43		AURKA_HUMAN (279-644): 3.21e-105: 326: 23.86
+	Sc
		766100 HSP7E_YEAST (1-644): 0: 895: 100.00		CLA4_YEAST (5-353): 7.42e-49: 185: 35.80
+	Hs
		501740 BIP_HUMAN (29-637): 1.81e-179: 526: 48.71		AKT1_HUMAN (245-654): 3.78e-123: 375: 19.81
+	Hs
		160348 BIP_HUMAN (29-637): 1.81e-179: 526: 48.71		AURKA_HUMAN (279-644): 3.21e-105: 326: 23.86