Interactor 1: SERA (P40054)
D-3-phosphoglycerate dehydrogenase 1 (3-PGDH 1) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399)
Gene: SER3

Interactor 2: SER33 (P40510)
D-3-phosphoglycerate dehydrogenase 2 (3-PGDH 2) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399)
Gene: SER33

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 11283351, 10688190, 11805826, 18719252, 20826334, 16554755, 37968396, unassigned1933, 16429126
Identification Methods two hybrid pooling approach, two hybrid, tandem affinity purification, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 2-Hacid_dh~2-Hacid_dh, 2-Hacid_dh~2-Hacid_dh_C, 2-Hacid_dh_C~2-Hacid_dh_C
Common GO terms GO:0004617 - phosphoglycerate dehydrogenase activity
GO:0005737 - cytoplasm
GO:0006564 - L-serine biosynthetic process
GO:0009070 - serine family amino acid biosynthetic process
GO:0051287 - NAD binding
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 469
Sc

1 469
+ Sc
+ Sc
+ Ec
+ At
+ Cj
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Ec
+ Dm
+ Sp
+ Hp
+ Cj

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Last updated: 15 Jul 2024