HitPredict

Interactor 1: TSC11 (P40061)
Target of rapamycin complex 2 subunit TSC11 (TORC2 subunit TSC11) (Adheres voraciously to TOR2 protein 3) (Temperature-sensitive CSG2 suppressor protein 11)
Gene: TSC11

Interactor 2: AVO2 (Q04749)
Target of rapamycin complex 2 subunit AVO2 (TORC2 subunit AVO2) (Adheres voraciously to TOR2 protein 2)
Gene: AVO2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	12408816, 16002396, 26028537, 30478248
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001558 - regulation of cell growth GO:0005774 - vacuolar membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030950 - establishment or maintenance of actin cytoskeleton polarity and 2 others more... GO:0031929 - TOR signaling GO:0031932 - TORC2 complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1430 Sc			1 426
+	Hs
		1163799 RICTR_HUMAN (329-1219): 0: 1023: 23.96		EHMT2_HUMAN (1-184): 2.09e-47: 176: 20.11
+	Hs
		883545 RICTR_HUMAN (329-1219): 0: 1023: 23.96		RIPK4_HUMAN (4-181): 3.59e-43: 163: 21.35
+	Hs
		257630 RICTR_HUMAN (329-1219): 0: 1023: 23.96		ANR17_HUMAN (18-425): 3.81e-42: 161: 12.53
+	Hs
		1163855 RICTR_HUMAN (329-1219): 0: 1023: 23.96		Q9H4D1_HUMAN (79-419): 6.2e-31: 127: 13.78
+	Hs
		1163741 RICTR_HUMAN (329-1219): 0: 1023: 23.96		ANKH1_HUMAN (146-425): 1.02e-25: 112: 11.43
+	Dm
		1362727 Q9VWJ6_DROME (338-713): 1.53e-106: 376: 17.86		ANKHM_DROME (3-131): 1.76e-23: 105: 18.61