HitPredict

Interactor 1: SLX8 (P40072)
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SLX8) (Synthetic lethal of unknown function protein 8)
Gene: SLX8

Interactor 2: SIZ2 (Q12216)
E3 SUMO-protein ligase SIZ2 (EC 2.3.2.-) (E3 SUMO-protein transferase SIZ2) (SAP and Miz-finger domain-containing protein 2)
Gene: NFI1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.594

The method score is based on:

Property Details
Experiments 18499666, 31519521
Identification Methods enzymatic study, two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0016925 - protein sumoylation
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 274
Sc

1 726
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024