HitPredict

Interactor 1: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Interactor 2: IRC20 (Q06554)
Uncharacterized ATP-dependent helicase IRC20 (EC 3.6.1.-) (Increased recombination centers protein 20)
Gene: IRC20

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 613 Sc			1 1556
+	Sc
		512851 SSB1_YEAST (1-613): 0: 1118: 99.35		IRC20_YEAST (1-1556): 0: 910: 100.00
+	Sc
		510266 SSB1_YEAST (1-613): 0: 1118: 99.35		SNF2_YEAST (882-1556): 6.24e-69: 259: 14.15
+	Sc
		769668 SSB2_YEAST (1-613): 0: 1122: 100.00		ULS1_YEAST (1093-1515): 4.06e-65: 246: 21.46
+	Sc
		513010 SSB1_YEAST (1-613): 0: 1118: 99.35		ULS1_YEAST (1093-1515): 4.06e-65: 246: 21.46
+	Sc
		699159 SSB2_YEAST (1-613): 0: 1122: 100.00		RAD5_YEAST (1088-1534): 6.44e-60: 228: 17.72
+	Sc
		510716 SSB1_YEAST (1-613): 0: 1118: 99.35		RAD5_YEAST (1088-1534): 6.44e-60: 228: 17.72
+	Sc
		769685 SSB2_YEAST (1-613): 0: 1122: 100.00		ISW2_YEAST (1247-1556): 6.02e-56: 215: 16.20
+	Sc
		513035 SSB1_YEAST (1-613): 0: 1118: 99.35		ISW2_YEAST (1247-1556): 6.02e-56: 215: 16.20
+	Sc
		510538 SSB1_YEAST (1-613): 0: 1118: 99.35		RAD16_YEAST (1239-1511): 6.46e-48: 187: 21.00
+	Sc
		687700 SSB2_YEAST (1-613): 0: 1122: 100.00		BTAF1_YEAST (1295-1541): 2.64e-30: 133: 17.15
+	Hs
		503984 HSP7C_HUMAN (5-612): 0: 897: 60.00		CHD3_HUMAN (925-1556): 1.26e-98: 354: 11.47
+	Sc
		510568 SSB1_YEAST (1-613): 0: 1118: 99.35		BTAF1_YEAST (1295-1541): 2.64e-30: 133: 17.15
+	Hs
		229290 HSP7C_HUMAN (5-612): 0: 897: 60.00		SMCA5_HUMAN (954-1555): 1.14e-98: 344: 11.88
+	Hs
		504094 HSP7C_HUMAN (5-612): 0: 897: 60.00		CHD4_HUMAN (912-1556): 9.85e-95: 341: 11.21
+	Hs
		713973 HS71L_HUMAN (5-612): 0: 893: 59.51		CHD4_HUMAN (912-1556): 9.85e-95: 341: 11.21
+	Sc
		697399 SSB2_YEAST (1-613): 0: 1122: 100.00		CHD1_YEAST (387-687): 2.43e-19: 97.2: 15.26
+	Sc
		510682 SSB1_YEAST (1-613): 0: 1118: 99.35		CHD1_YEAST (387-687): 2.43e-19: 97.2: 15.26
+	Hs
		503711 HSP7C_HUMAN (5-612): 0: 897: 60.00		SMCA2_HUMAN (858-1556): 5.63e-84: 307: 12.16
+	Hs
		504080 HSP7C_HUMAN (5-612): 0: 897: 60.00		HLTF_HUMAN (266-712): 1.61e-80: 290: 21.62
+	Hs
		871587 HSP72_HUMAN (4-612): 0: 888: 60.13		ERC6L_HUMAN (303-721): 2.36e-28: 126: 14.73