Interactor 1: IL6RB (P40189)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: IL6ST
Interactor 2: IL6RB (P40189)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: IL6ST
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.68 | 1.00 | 0.827 |
The method score is based on:
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | fn3~fn3, IL6Ra-bind~fn3, IL6Ra-bind~IL6Ra-bind, IL6Ra-bind~Lep_receptor_Ig |
Common GO terms | GO:0002675 - positive regulation of acute inflammatory response GO:0002821 - positive regulation of adaptive immune response GO:0004896 - cytokine receptor activity GO:0004897 - ciliary neurotrophic factor receptor activity GO:0004915 - interleukin-6 receptor activity and 46 others more... |
Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024