Interactor 1: IL6RB (P40189)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (CDw130) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: IL6ST

Interactor 2: OSMR (Q99650)
Oncostatin-M-specific receptor subunit beta (Interleukin-31 receptor subunit beta) (IL-31 receptor subunit beta) (IL-31R subunit beta) (IL-31R-beta) (IL-31RB)
Gene: OSMR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 8999038, 24501689
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, IL6Ra-bind~fn3
Common GO terms GO:0002675 - positive regulation of acute inflammatory response
GO:0004896 - cytokine receptor activity
GO:0005127 - ciliary neurotrophic factor receptor binding
GO:0005886 - plasma membrane
GO:0005900 - oncostatin-M receptor complex
and 8 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 918
Hs

1 979
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Last updated: 15 Jul 2024