HitPredict

Interactor 1: CSF3R (P40223)
Granulocyte colony-stimulating factor receptor (G-CSF receptor) (G-CSF-R) (CD antigen CD114)
Gene: CSF3R

Interactor 2: GRB2 (Q60631)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	9824671
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~fn3
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 837 Mm			1 217
+	Hs
		924809 CSF3R_HUMAN (1-837): 5.56e-157: 481: 60.60		GRB2_HUMAN (1-217): 6.92e-74: 224: 99.54
+	Mm
		411919 CSF3R_MOUSE (1-837): 3.29e-171: 518: 100.00		LCK_MOUSE (3-202): 5.14e-38: 139: 28.44
+	Mm
		435879 CSF3R_MOUSE (1-837): 3.29e-171: 518: 100.00		HCK_MOUSE (136-215): 1.06e-10: 62.3: 26.83
+	Hs
		770194 IL6RB_HUMAN (7-814): 3.29e-104: 344: 22.59		GRB2_HUMAN (1-217): 6.92e-74: 224: 99.54
+	Hs
		442875 CSF3R_HUMAN (1-837): 5.56e-157: 481: 60.60		HCK_HUMAN (116-215): 1.24e-11: 64.9: 19.61
+	Hs
		433961 CSF3R_HUMAN (1-837): 5.56e-157: 481: 60.60		LYN_HUMAN (136-215): 4.12e-10: 60.7: 24.39
+	Hs
		548653 IL6RB_HUMAN (7-814): 3.29e-104: 344: 22.59		VAV_HUMAN (3-60): 1.14e-15: 76.9: 43.10
+	Hs
		442787 IL6RB_HUMAN (7-814): 3.29e-104: 344: 22.59		HCK_HUMAN (116-215): 1.24e-11: 64.9: 19.61
+	Hs
		412016 PTPRD_HUMAN (123-834): 3.65e-69: 252: 11.84		FYN_HUMAN (161-215): 4.88e-13: 69.2: 31.58
+	Hs
		817315 LEPR_HUMAN (129-323): 2.86e-15: 82.6: 17.39		GRB2_HUMAN (1-217): 6.92e-74: 224: 99.54
+	Hs
		411565 PTPRF_HUMAN (26-574): 9.77e-42: 167: 12.08		LCK_HUMAN (3-202): 7.66e-38: 138: 28.91
+	Hs
		548629 PRLR_HUMAN (122-342): 1.27e-51: 193: 24.44		VAV_HUMAN (3-60): 1.14e-15: 76.9: 43.10
+	Hs
		560471 PRLR_HUMAN (122-342): 1.27e-51: 193: 24.44		VAV2_HUMAN (3-56): 6.02e-11: 63.1: 38.18
+	Dm
		53796 A1Z921_DROME (10-514): 5.06e-38: 155: 12.64		ABL_DROME (4-135): 1.01e-22: 97.4: 37.68
+	Mm
		56907 PTPRF_MOUSE (9-574): 1.08e-46: 183: 13.57		FYN_MOUSE (161-215): 4.88e-13: 69.2: 31.58
+	Dm
		337644 LAR_DROME (31-598): 5.6e-37: 152: 11.95		ABL_DROME (4-135): 1.01e-22: 97.4: 37.68
+	Hs
		411959 PTPRF_HUMAN (26-574): 9.77e-42: 167: 12.08		FYN_HUMAN (161-215): 4.88e-13: 69.2: 31.58
+	Hs
		433804 SDK2_HUMAN (22-834): 6.07e-38: 155: 9.63		LYN_HUMAN (136-215): 4.12e-10: 60.7: 24.39
+	Hs
		557632 DCC_HUMAN (115-383): 1.2e-14: 80.5: 9.63		NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14
+	Hs
		434019 ROBO2_HUMAN (230-820): 1.34e-21: 103: 10.24		LYN_HUMAN (136-215): 4.12e-10: 60.7: 24.39