HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 340
+	Hs
		921697 TCPH_HUMAN (2-530): 0: 576: 27.93		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		921038 TCPH_HUMAN (2-530): 0: 576: 27.93		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		770778 TCPZ_HUMAN (1-531): 0: 573: 100.00		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		1202777 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18
+	Hs
		770916 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18
+	Sc
		579424 TCPZ_YEAST (3-530): 0: 579: 56.75		GBB_YEAST (2-340): 1.33e-76: 243: 36.53
+	Hs
		770974 TCPZ_HUMAN (1-531): 0: 573: 100.00		SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30
+	Hs
		903467 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		770771 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93
+	Hs
		154696 TCPH_HUMAN (2-530): 0: 576: 27.93		GNB5_HUMAN (129-340): 1.35e-45: 161: 21.46
+	Hs
		154659 TCPZ_HUMAN (1-531): 0: 573: 100.00		GNB5_HUMAN (129-340): 1.35e-45: 161: 21.46
+	Hs
		154662 TCPG_HUMAN (3-528): 0: 559: 27.96		GNB5_HUMAN (129-340): 1.35e-45: 161: 21.46
+	Hs
		1306704 TCPH_HUMAN (2-530): 0: 576: 27.93		NLE1_HUMAN (3-124): 6.68e-32: 126: 25.41
+	Hs
		771069 TCPZ_HUMAN (1-531): 0: 573: 100.00		NLE1_HUMAN (3-124): 6.68e-32: 126: 25.41
+	Hs
		1240450 TCPH_HUMAN (2-530): 0: 576: 27.93		POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24
+	Hs
		770932 TCPZ_HUMAN (1-531): 0: 573: 100.00		POC1A_HUMAN (10-125): 4.11e-27: 112: 17.24
+	Hs
		792942 TCPG_HUMAN (3-528): 0: 559: 27.96		LIS1_HUMAN (259-340): 1.35e-18: 87.8: 23.17
+	Hs
		197078 TCPH_HUMAN (2-530): 0: 576: 27.93		PRP4_HUMAN (51-253): 1.06e-12: 70.5: 25.85
+	Hs
		196964 TCPZ_HUMAN (1-531): 0: 573: 100.00		PRP4_HUMAN (51-253): 1.06e-12: 70.5: 25.85
+	Hs
		196973 TCPG_HUMAN (3-528): 0: 559: 27.96		PRP4_HUMAN (51-253): 1.06e-12: 70.5: 25.85