HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: ERCC8 (Q13216)
DNA excision repair protein ERCC-8 (Cockayne syndrome WD repeat protein CSA)
Gene: ERCC8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29531219, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 396
+	Hs
		1028020 TCPH_HUMAN (2-530): 0: 576: 27.93		ERCC8_HUMAN (1-396): 7.48e-87: 270: 100.00
+	Hs
		1306645 TCPH_HUMAN (2-530): 0: 576: 27.93		TBL1Y_HUMAN (2-321): 1.67e-67: 224: 18.24
+	Hs
		770968 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBXW7_HUMAN (128-395): 4.9e-60: 208: 13.76
+	Hs
		903467 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Hs
		770771 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5_HUMAN (218-396): 2.25e-46: 163: 20.44
+	Ce
		804396 TCPZ_CAEEL (1-530): 0: 671: 66.23		LIN53_CAEEL (98-276): 1.11e-09: 61.6: 25.82
+	At
		1341262 TCPZA_ARATH (3-530): 0: 664: 62.29		PEX7_ARATH (98-229): 1.28e-11: 67: 32.33
+	Hs
		1202777 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	Hs
		770916 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5B_HUMAN (220-396): 1.61e-42: 153: 18.99
+	At
		1226315 TCPZB_ARATH (3-530): 0: 655: 62.29		PEX7_ARATH (98-229): 1.28e-11: 67: 32.33
+	Hs
		1240450 TCPH_HUMAN (2-530): 0: 576: 27.93		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Hs
		770932 TCPZ_HUMAN (1-531): 0: 573: 100.00		POC1A_HUMAN (4-130): 3.18e-24: 105: 13.38
+	Hs
		1306704 TCPH_HUMAN (2-530): 0: 576: 27.93		NLE1_HUMAN (3-71): 4.91e-16: 81.3: 18.57
+	Hs
		1083362 TCPH_HUMAN (2-530): 0: 576: 27.93		RBBP7_HUMAN (129-368): 4.26e-15: 78.3: 19.22
+	Hs
		770853 TCPZ_HUMAN (1-531): 0: 573: 100.00		RBBP7_HUMAN (129-368): 4.26e-15: 78.3: 19.22
+	Sc
		761103 TCPZ_YEAST (3-530): 0: 579: 56.75		RAD28_YEAST (98-272): 1.54e-12: 70.9: 26.80
+	Hs
		1017427 TCPH_HUMAN (2-530): 0: 576: 27.93		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		197078 TCPH_HUMAN (2-530): 0: 576: 27.93		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27
+	Hs
		770805 TCPZ_HUMAN (1-531): 0: 573: 100.00		CDC20_HUMAN (69-352): 8.11e-11: 65.5: 23.81
+	Hs
		196964 TCPZ_HUMAN (1-531): 0: 573: 100.00		PRP4_HUMAN (89-272): 1.17e-10: 65.1: 26.27