HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: HECD3 (Q5T447)
E3 ubiquitin-protein ligase HECTD3 (EC 2.3.2.26) (HECT domain-containing protein 3) (HECT-type E3 ubiquitin transferase HECTD3)
Gene: HECTD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 531 Hs			1 861
+	Hs
		1133254 TCPH_HUMAN (2-530): 0: 576: 27.93		HECD3_HUMAN (1-861): 0: 1137: 100.00
+	Hs
		1133246 TCPW_HUMAN (1-530): 0: 542: 85.85		HECD3_HUMAN (1-861): 0: 1137: 100.00
+	Hs
		125246 TCPG_HUMAN (3-528): 0: 559: 27.96		WWP2_HUMAN (321-855): 1.45e-172: 523: 17.74
+	Hs
		1306694 TCPH_HUMAN (2-530): 0: 576: 27.93		SMUF1_HUMAN (336-855): 2.1e-167: 506: 17.88
+	Hs
		771057 TCPZ_HUMAN (1-531): 0: 573: 100.00		SMUF1_HUMAN (336-855): 2.1e-167: 506: 17.88
+	Hs
		1192186 TCPH_HUMAN (2-530): 0: 576: 27.93		HUWE1_HUMAN (329-854): 6.82e-152: 496: 19.78
+	Hs
		125243 TCPE_HUMAN (3-528): 0: 548: 30.47		WWP2_HUMAN (321-855): 1.45e-172: 523: 17.74
+	Hs
		770908 TCPZ_HUMAN (1-531): 0: 573: 100.00		HUWE1_HUMAN (329-854): 6.82e-152: 496: 19.78
+	Hs
		125607 TCPW_HUMAN (1-530): 0: 542: 85.85		WWP2_HUMAN (321-855): 1.45e-172: 523: 17.74
+	Hs
		826741 TCPG_HUMAN (3-528): 0: 559: 27.96		HUWE1_HUMAN (329-854): 6.82e-152: 496: 19.78
+	Hs
		821288 TCPE_HUMAN (3-528): 0: 548: 30.47		HUWE1_HUMAN (329-854): 6.82e-152: 496: 19.78
+	Sc
		761062 TCPZ_YEAST (3-530): 0: 579: 56.75		TOM1_YEAST (436-849): 1.84e-118: 398: 23.61
+	Sc
		792404 TCPH_YEAST (2-528): 0: 543: 25.84		TOM1_YEAST (436-849): 1.84e-118: 398: 23.61
+	Sc
		760801 TCPG_YEAST (2-527): 0: 539: 26.16		TOM1_YEAST (436-849): 1.84e-118: 398: 23.61
+	Hs
		1072710 TCPH_HUMAN (2-530): 0: 576: 27.93		UBE3C_HUMAN (495-845): 2.66e-20: 99: 27.64
+	Hs
		1061574 TCPH_HUMAN (2-530): 0: 576: 27.93		CUL7_HUMAN (245-370): 1.55e-18: 93.6: 40.63
+	Hs
		770836 TCPZ_HUMAN (1-531): 0: 573: 100.00		CUL7_HUMAN (245-370): 1.55e-18: 93.6: 40.63
+	Hs
		826666 TCPG_HUMAN (3-528): 0: 559: 27.96		CUL7_HUMAN (245-370): 1.55e-18: 93.6: 40.63
+	Hs
		821216 TCPE_HUMAN (3-528): 0: 548: 30.47		CUL7_HUMAN (245-370): 1.55e-18: 93.6: 40.63