HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: HDA11 (Q96DB2)
Histone deacetylase 11 (HD11) (EC 3.5.1.98)
Gene: HDAC11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 347
+	Hs
		1038670 TCPH_HUMAN (2-530): 0: 576: 27.93		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		770823 TCPZ_HUMAN (1-531): 0: 573: 100.00		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Mm
		945920 TCPH_MOUSE (2-530): 0: 582: 27.75		HDAC4_MOUSE (1-341): 6.57e-129: 396: 21.60
+	Hs
		826651 TCPG_HUMAN (3-528): 0: 559: 27.96		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Sc
		693019 TCPZ_YEAST (3-530): 0: 579: 56.75		RPD3_YEAST (2-340): 1.99e-131: 383: 22.95
+	Hs
		826813 TCPG_HUMAN (3-528): 0: 559: 27.96		HDA11_HUMAN (1-347): 1.17e-140: 403: 100.00
+	Hs
		821200 TCPE_HUMAN (3-528): 0: 548: 30.47		HDAC1_HUMAN (13-330): 8.87e-140: 407: 22.89
+	Hs
		177367 TCPH_HUMAN (2-530): 0: 576: 27.93		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		770965 TCPZ_HUMAN (1-531): 0: 573: 100.00		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		177216 TCPZ_HUMAN (1-531): 0: 573: 100.00		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Sc
		761039 TCPZ_YEAST (3-530): 0: 579: 56.75		HOS2_YEAST (3-331): 6.58e-124: 365: 21.43
+	Hs
		821140 TCPE_HUMAN (3-528): 0: 548: 30.47		HDAC4_HUMAN (1-341): 1.28e-127: 393: 20.53
+	Hs
		826803 TCPG_HUMAN (3-528): 0: 559: 27.96		HDAC2_HUMAN (13-330): 4.9e-128: 376: 22.89
+	Hs
		177233 TCPG_HUMAN (3-528): 0: 559: 27.96		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		177231 TCPE_HUMAN (3-528): 0: 548: 30.47		HDAC3_HUMAN (14-340): 3.7e-128: 375: 20.47
+	Hs
		1306720 TCPH_HUMAN (2-530): 0: 576: 27.93		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Hs
		826927 TCPG_HUMAN (3-528): 0: 559: 27.96		HDAC6_HUMAN (18-346): 8.68e-95: 307: 21.31
+	Sp
		140559 TCPZ_SCHPO (7-530): 0: 639: 63.07		PHD1_SCHPO (134-307): 1.94e-15: 79: 31.69
+	Sp
		140638 TCPH_SCHPO (3-527): 0: 560: 26.27		PHD1_SCHPO (134-307): 1.94e-15: 79: 31.69
+	Sp
		140519 TCPG_SCHPO (2-527): 0: 555: 28.76		PHD1_SCHPO (134-307): 1.94e-15: 79: 31.69