HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: STRAB (Q9C0K7)
STE20-related kinase adapter protein beta (STRAD beta) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein) (CALS-21) (ILP-interacting protein) (Pseudokinase ALS2CR2)
Gene: STRADB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 418
+	Hs
		625579 TCPH_HUMAN (2-530): 0: 576: 27.93		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		625190 TCPZ_HUMAN (1-531): 0: 573: 100.00		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		1306668 TCPH_HUMAN (2-530): 0: 576: 27.93		STRAB_HUMAN (1-418): 5.39e-125: 369: 98.33
+	Hs
		625228 TCPG_HUMAN (3-528): 0: 559: 27.96		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		415042 TCPH_HUMAN (2-530): 0: 576: 27.93		CDK1_HUMAN (55-374): 1.01e-123: 361: 20.56
+	Hs
		826872 TCPG_HUMAN (3-528): 0: 559: 27.96		STRAB_HUMAN (1-418): 5.39e-125: 369: 98.33
+	Hs
		625220 TCPE_HUMAN (3-528): 0: 548: 30.47		CDK2_HUMAN (55-375): 1.38e-130: 379: 18.69
+	Hs
		414817 TCPE_HUMAN (3-528): 0: 548: 30.47		CDK1_HUMAN (55-374): 1.01e-123: 361: 20.56
+	Hs
		826737 TCPG_HUMAN (3-528): 0: 559: 27.96		STRAA_HUMAN (20-388): 1.16e-113: 341: 46.61
+	Hs
		960322 TCPH_HUMAN (2-530): 0: 576: 27.93		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		770793 TCPZ_HUMAN (1-531): 0: 573: 100.00		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		1023098 TCPH_HUMAN (2-530): 0: 576: 27.93		STK4_HUMAN (58-373): 3.33e-104: 318: 25.00
+	Hs
		1306764 TCPH_HUMAN (2-530): 0: 576: 27.93		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Hs
		826623 TCPG_HUMAN (3-528): 0: 559: 27.96		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		771114 TCPZ_HUMAN (1-531): 0: 573: 100.00		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Hs
		1306717 TCPH_HUMAN (2-530): 0: 576: 27.93		STK26_HUMAN (58-390): 2.83e-99: 303: 26.13
+	Hs
		826636 TCPG_HUMAN (3-528): 0: 559: 27.96		STK4_HUMAN (58-373): 3.33e-104: 318: 25.00
+	Hs
		821173 TCPE_HUMAN (3-528): 0: 548: 30.47		CDK5_HUMAN (55-375): 1.04e-108: 323: 16.77
+	Hs
		826963 TCPG_HUMAN (3-528): 0: 559: 27.96		STK24_HUMAN (42-390): 2.33e-100: 307: 25.22
+	Sc
		439656 TCPZ_YEAST (3-530): 0: 579: 56.75		SPS1_YEAST (58-372): 2.8e-24: 106: 29.06