HitPredict

Interactor 1: PSB1 (P40304)
Proteasome subunit beta type-1 (Proteasome 26 kDa subunit)
Gene: Prosbeta6

Interactor 2: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 235 Dm			1 433
+	Hs
		730214 PSB3_HUMAN (23-235): 6.12e-83: 247: 26.51		PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69
+	Dm
		1181072 PSB3_DROME (23-235): 2.21e-80: 241: 27.91		Q7KMQ0_DROME (1-433): 3.2e-145: 422: 100.00
+	Hs
		730228 PSA6_HUMAN (2-234): 3.49e-72: 221: 19.92		PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69
+	Hs
		156240 PSA7_HUMAN (5-235): 5.48e-71: 218: 15.48		PRS7_HUMAN (1-433): 1.46e-144: 420: 91.69
+	Dm
		186172 PSB3_DROME (23-235): 2.21e-80: 241: 27.91		PRS8_DROME (50-430): 1.1e-124: 369: 48.56
+	Hs
		831972 PSB3_HUMAN (23-235): 6.12e-83: 247: 26.51		PRS8_HUMAN (27-430): 2.52e-121: 360: 45.79
+	Sc
		632478 PSB3_YEAST (23-235): 1.81e-73: 223: 29.77		PRS7_YEAST (1-433): 9.76e-128: 379: 67.24
+	Hs
		831973 PSB3_HUMAN (23-235): 6.12e-83: 247: 26.51		PRS10_HUMAN (34-429): 5.68e-118: 351: 41.86
+	Dm
		186106 PSB1_DROME (1-235): 2.61e-74: 227: 100.00		PRS8_DROME (50-430): 1.1e-124: 369: 48.56
+	Hs
		831971 PSB3_HUMAN (23-235): 6.12e-83: 247: 26.51		PRS4_HUMAN (1-430): 1e-116: 349: 40.28
+	Dm
		820535 PSB3_DROME (23-235): 2.21e-80: 241: 27.91		PRS4_DROME (1-430): 3.22e-118: 353: 38.89
+	Dm
		1359424 PSB3_DROME (23-235): 2.21e-80: 241: 27.91		Q9V405_DROME (29-425): 4.38e-118: 352: 37.87
+	Dm
		1376594 PSB3_DROME (23-235): 2.21e-80: 241: 27.91		Q9W414_DROME (33-429): 1.01e-116: 348: 43.00
+	Hs
		893640 PSA6_HUMAN (2-234): 3.49e-72: 221: 19.92		PRS8_HUMAN (27-430): 2.52e-121: 360: 45.79
+	Dm
		771398 PSB1_DROME (1-235): 2.61e-74: 227: 100.00		PRS4_DROME (1-430): 3.22e-118: 353: 38.89
+	Dm
		771413 PSB1_DROME (1-235): 2.61e-74: 227: 100.00		Q9V405_DROME (29-425): 4.38e-118: 352: 37.87
+	Dm
		771434 PSB1_DROME (1-235): 2.61e-74: 227: 100.00		Q9W414_DROME (33-429): 1.01e-116: 348: 43.00
+	Sc
		632499 PSB3_YEAST (23-235): 1.81e-73: 223: 29.77		PRS8_YEAST (43-430): 4.52e-117: 349: 45.36
+	Hs
		893642 PSA6_HUMAN (2-234): 3.49e-72: 221: 19.92		PRS10_HUMAN (34-429): 5.68e-118: 351: 41.86
+	Hs
		893639 PSA6_HUMAN (2-234): 3.49e-72: 221: 19.92		PRS4_HUMAN (1-430): 1e-116: 349: 40.28