Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.90 0.888

The method score is based on:

Property Details
Experiments 26211615, 20300531, 30903204, 21942715, 16407835, 21625219
Identification Methods two hybrid, affinity chromatography technology, enzymatic study, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains VHL~VHL, VHL~VHL_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000902 - cell morphogenesis
GO:0003711 - transcription elongation factor activity
GO:0003714 - transcription corepressor activity
GO:0004842 - ubiquitin-protein transferase activity
and 31 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024