Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL
Interactor 2: RBX1 (P62877)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (Protein ZYP) (RING finger protein 75) (RING-box protein 1) (Rbx1) (Regulator of cullins 1) (ROC1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed (E3 ubiquitin-protein transferase RBX1, N-terminally processed)]
Gene: RBX1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.760 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30349055, 33504946, 26735018, 17353931, 33137104, 33567268, 36813923, 16325183, 12048197, 12604794, 16503656, 16261165, 15601820, 23401859, 24469044 |
| Identification Methods | affinity chromatography technology, pull down, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 1 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
