HitPredict

Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: CO4A3 (Q01955)
Collagen alpha-3(IV) chain (Goodpasture antigen) [Cleaved into: Tumstatin]
Gene: COL4A3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	21942715, 17339318
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 1670
+	Hs
		771960 VHL_HUMAN (1-213): 3.45e-146: 407: 100.00		CO4A6_HUMAN (352-1500): 4.32e-111: 392: 32.11
+	Hs
		441058 VHL_HUMAN (1-213): 3.45e-146: 407: 100.00		CO4A2_HUMAN (3-695): 1.01e-75: 281: 33.76
+	Hs
		666797 VHL_HUMAN (1-213): 3.45e-146: 407: 100.00		CO4A5_HUMAN (1-1045): 8.57e-57: 220: 33.39
+	Hs
		358658 VHL_HUMAN (1-213): 3.45e-146: 407: 100.00		CO4A1_HUMAN (2-424): 4.02e-30: 133: 30.58