Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL
Interactor 2: HIF3A (Q9Y2N7)
Hypoxia-inducible factor 3-alpha (HIF-3-alpha) (HIF3-alpha) (Basic-helix-loop-helix-PAS protein MOP7) (Class E basic helix-loop-helix protein 17) (bHLHe17) (HIF3-alpha-1) (Inhibitory PAS domain protein) (IPAS) (Member of PAS protein 7) (PAS domain-containing protein 7)
Gene: HIF3A
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.52 | 1.00 | 0.724 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12538644 |
Identification Methods | pull down, affinity chromatography technology |
Interaction Type | direct interaction, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | HIF-1~VHL |
Common GO terms | GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0071456 - cellular response to hypoxia |
Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024