HitPredict

Interactor 1: VHL (P40338)
von Hippel-Lindau disease tumor suppressor (pVHL)
Gene: VHL

Interactor 2: RBX1 (P62878)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (RING finger protein 75) (RING-box protein 1) (Rbx1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed]
Gene: RBX1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

The method score is based on:

Property	Details
Experiments	23990666, 15601820
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016567 - protein ubiquitination GO:0030163 - protein catabolic process GO:0030891 - VCB complex and 3 others more... GO:0031462 - Cul2-RING ubiquitin ligase complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:0044877 - protein-containing complex binding
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	181
Mm

1	108

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024