Interactor 1: IRS1 (P35568)
Insulin receptor substrate 1 (IRS-1)
Gene: IRS1
Interactor 2: NUMB (P49757)
Protein numb homolog (h-Numb) (Protein S171)
Gene: NUMB
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.58 | 0.60 | 0.594 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25814554, unassigned1126 |
| Identification Methods | two hybrid, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
