HitPredict

Interactor 1: EXD (P40427)
Homeobox protein extradenticle (Dpbx)
Gene: EXD

Interactor 2: Q7KS77 (Q7KS77)
Ladybird early (MIP30310p)
Gene: lbe

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	30247122
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeobox_KN~Homeodomain
Common GO terms	GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0007525 - somatic muscle development GO:0042659 - regulation of cell fate specification
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Dm			1 479
+	Dm
		367183 EXD_DROME (1-376): 6.47e-115: 340: 100.00		ANTP_DROME (213-420): 4.7e-32: 128: 20.19
+	Dm
		773222 EXD_DROME (1-376): 6.47e-115: 340: 100.00		UBX_DROME (216-417): 2.77e-27: 114: 17.79
+	Mm
		192602 PBX3_MOUSE (1-368): 4.2e-100: 305: 67.38		HXB5_MOUSE (218-413): 7.03e-35: 133: 25.00
+	Hs
		447226 PBX1_HUMAN (2-375): 1.95e-99: 303: 68.72		HXB5_HUMAN (218-413): 2.95e-35: 133: 25.00
+	Hs
		679069 PBX3_HUMAN (1-368): 2.94e-100: 305: 67.38		TLX1_HUMAN (303-417): 8.16e-31: 123: 38.02
+	Mm
		192604 PBX3_MOUSE (1-368): 4.2e-100: 305: 67.38		HXA9_MOUSE (180-419): 1.2e-30: 121: 17.07
+	Mm
		192607 PBX3_MOUSE (1-368): 4.2e-100: 305: 67.38		HXC6_MOUSE (209-411): 7.91e-31: 120: 21.46
+	Hs
		678851 PBX3_HUMAN (1-368): 2.94e-100: 305: 67.38		HXA9_HUMAN (185-419): 5.3e-30: 119: 17.70
+	Hs
		174011 PBX1_HUMAN (2-375): 1.95e-99: 303: 68.72		SHOX_HUMAN (352-415): 3.05e-30: 120: 45.31
+	Mm
		192603 PBX3_MOUSE (1-368): 4.2e-100: 305: 67.38		HXA6_MOUSE (208-413): 6.77e-30: 118: 18.27
+	Hs
		238102 PBX3_HUMAN (1-368): 2.94e-100: 305: 67.38		LMX1B_HUMAN (279-477): 1.61e-28: 118: 18.50
+	Mm
		192609 PBX3_MOUSE (1-368): 4.2e-100: 305: 67.38		HXD10_MOUSE (219-425): 1.55e-28: 117: 23.81
+	Hs
		567798 PBX3_HUMAN (1-368): 2.94e-100: 305: 67.38		HXB8_HUMAN (227-449): 2.78e-29: 117: 18.22
+	Hs
		678849 PBX1_HUMAN (2-375): 1.95e-99: 303: 68.72		HXA9_HUMAN (185-419): 5.3e-30: 119: 17.70
+	Hs
		238100 PBX1_HUMAN (2-375): 1.95e-99: 303: 68.72		LMX1B_HUMAN (279-477): 1.61e-28: 118: 18.50
+	Hs
		453053 PBX1_HUMAN (2-375): 1.95e-99: 303: 68.72		HXB7_HUMAN (228-413): 3.99e-30: 118: 19.80
+	Hs
		567797 PBX1_HUMAN (2-375): 1.95e-99: 303: 68.72		HXB8_HUMAN (227-449): 2.78e-29: 117: 18.22
+	Mm
		192606 PBX3_MOUSE (1-368): 4.2e-100: 305: 67.38		HXD4_MOUSE (308-411): 3.54e-28: 114: 35.51
+	Hs
		446865 PBX1_HUMAN (2-375): 1.95e-99: 303: 68.72		HXD4_HUMAN (208-454): 2.22e-27: 112: 18.62
+	Dm
		611842 EXD_DROME (1-376): 6.47e-115: 340: 100.00		BAGP_DROME (352-410): 5.23e-10: 63.2: 55.93