HitPredict

Interactor 1: MLP2 (P40457)
Protein MLP2 (Myosin-like protein 2)
Gene: MLP2

Interactor 2: NUP57 (P48837)
Nucleoporin NUP57 (Nuclear pore protein NUP57)
Gene: NUP57

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	24500206, 33333025, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0006606 - protein import into nucleus GO:0006913 - nucleocytoplasmic transport GO:0017056 - structural constituent of nuclear pore
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1679 Sc			1 541
+	Sc
		773951 MLP2_YEAST (1-1679): 1.53e-108: 384: 100.00		NU145_YEAST (4-393): 1.5e-42: 165: 21.52
+	Sc
		773930 MLP2_YEAST (1-1679): 1.53e-108: 384: 100.00		NU159_YEAST (5-321): 5.81e-20: 96.3: 15.46
+	Hs
		1188238 CP250_HUMAN (319-1660): 1.16e-44: 180: 10.75		NUP54_HUMAN (159-535): 2.87e-90: 288: 17.83
+	Dm
		53359 TPR_DROME (26-1457): 1.46e-110: 393: 16.97		NUP98_DROME (2-329): 1.49e-11: 69.7: 11.49
+	Sc
		773975 MLP2_YEAST (1-1679): 1.53e-108: 384: 100.00		NUP49_YEAST (45-298): 1.04e-09: 62.8: 23.11
+	Sc
		773978 MLP2_YEAST (1-1679): 1.53e-108: 384: 100.00		NU116_YEAST (1-282): 6.89e-09: 60.8: 22.95
+	Sc
		822989 MLP1_YEAST (1-1385): 4.84e-33: 142: 9.98		NUP57_YEAST (1-541): 1.51e-93: 297: 100.00
+	Sc
		830672 MLP1_YEAST (1-1385): 4.84e-33: 142: 9.98		NU145_YEAST (4-393): 1.5e-42: 165: 21.52
+	Hs
		518842 TPR_HUMAN (1-1471): 8.73e-45: 181: 9.95		NUP98_HUMAN (68-329): 1.41e-14: 79.4: 16.10
+	Hs
		518828 TPR_HUMAN (1-1471): 8.73e-45: 181: 9.95		NU214_HUMAN (17-255): 5.03e-10: 64.6: 22.76
+	Hs
		518839 TPR_HUMAN (1-1471): 8.73e-45: 181: 9.95		NU153_HUMAN (4-290): 7.4e-09: 60.8: 15.46
+	Sc
		774366 MLP1_YEAST (1-1385): 4.84e-33: 142: 9.98		NU159_YEAST (5-321): 5.81e-20: 96.3: 15.46
+	Hs
		253766 MYH13_HUMAN (1010-1677): 6.59e-23: 109: 8.75		AUXI_HUMAN (4-290): 1.47e-26: 116: 15.84
+	Sc
		970945 MLP1_YEAST (1-1385): 4.84e-33: 142: 9.98		NU100_YEAST (12-279): 1.74e-12: 72.4: 29.41
+	Sc
		697993 MLP1_YEAST (1-1385): 4.84e-33: 142: 9.98		SLA1_YEAST (3-292): 4.47e-12: 71.2: 16.43
+	Hs
		231276 MYH6_HUMAN (1145-1676): 1.39e-16: 88.5: 9.65		GANP_HUMAN (6-291): 5.72e-27: 118: 14.00
+	Sc
		969351 MLP1_YEAST (1-1385): 4.84e-33: 142: 9.98		NUP49_YEAST (45-298): 1.04e-09: 62.8: 23.11
+	Sc
		970946 MLP1_YEAST (1-1385): 4.84e-33: 142: 9.98		NU116_YEAST (1-282): 6.89e-09: 60.8: 22.95
+	Hs
		231304 PLEC_HUMAN (1-684): 9.16e-14: 79.6: 8.47		GANP_HUMAN (6-291): 5.72e-27: 118: 14.00
+	Hs
		148539 CTRO_HUMAN (13-697): 1.8e-13: 78.1: 14.33		NU153_HUMAN (4-290): 7.4e-09: 60.8: 15.46