HitPredict

Interactor 1: LYS12 (P40495)
Homoisocitrate dehydrogenase, mitochondrial (HIcDH) (EC 1.1.1.87)
Gene: LYS12

Interactor 2: COPB2 (P41811)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP)
Gene: SEC27

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.50	0.565

Property	Details
Experiments	11805837, 16429126
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 371 Sc			1 889
+	Sc
		657079 IDH2_YEAST (2-371): 2.68e-141: 407: 33.95		COPB2_YEAST (1-853): 0: 621: 100.00
+	Sc
		660918 IDH1_YEAST (3-371): 2.95e-138: 399: 34.41		COPB2_YEAST (1-853): 0: 621: 100.00
+	Sc
		378362 LEU3_YEAST (25-371): 7.77e-113: 335: 31.25		COPB2_YEAST (1-853): 0: 621: 100.00
+	Sc
		774654 LYS12_YEAST (1-371): 1.6e-151: 433: 100.00		COPA_YEAST (3-887): 8.6e-161: 503: 20.34
+	Sc
		657092 IDH2_YEAST (2-371): 2.68e-141: 407: 33.95		COPA_YEAST (3-887): 8.6e-161: 503: 20.34
+	Sc
		378376 LEU3_YEAST (25-371): 7.77e-113: 335: 31.25		COPA_YEAST (3-887): 8.6e-161: 503: 20.34
+	Hs
		837722 IDH3A_HUMAN (13-371): 1.8e-149: 428: 35.36		WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11
+	Hs
		822452 IDHP_HUMAN (3-371): 1.69e-123: 365: 17.32		WDR5_HUMAN (342-624): 6.55e-49: 178: 11.11