Interactor 1: COPE (P40509)
Coatomer subunit epsilon (Epsilon-coat protein) (Epsilon-COP)
Gene: SEC28

Interactor 2: COPA (P53622)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (Retrieval from endoplasmic reticulum protein 1) (Secretory protein 22) (Suppressor of osmo-sensitivity 1)
Gene: COP1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 20534429, 11805826, 11805837, 16429126, 22940862, 21435344, 16554755, 31712447, 37968396, 35904239, 22538654, 10921873, 14699056
Identification Methods molecular sieving, x-ray crystallography, ion exchange chromatography, cosedimentation in solution, pull down, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains COPI_C~Coatomer_E
Common GO terms GO:0000139 - Golgi membrane
GO:0005198 - structural molecule activity
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0006891 - intra-Golgi vesicle-mediated transport
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 296
Sc

1 1201
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024