HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: CI072 (Q96LT7)
Guanine nucleotide exchange factor C9orf72
Gene: C9orf72

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37317656, 29950492
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0098978 - glutamatergic synapse GO:0099523 - presynaptic cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 481
+	Hs
		1368863 RBP56_HUMAN (42-460): 2.96e-42: 161: 48.10		CI072_HUMAN (1-481): 0: 901: 100.00
+	Hs
		1033155 EWS_HUMAN (3-451): 4.67e-30: 126: 31.05		CI072_HUMAN (1-481): 0: 901: 100.00
+	Hs
		1102064 PABP4_HUMAN (280-379): 4.84e-13: 73.5: 22.00		CI072_HUMAN (1-481): 0: 901: 100.00
+	Hs
		550419 PABP1_HUMAN (281-379): 1.43e-11: 68.9: 22.22		CI072_HUMAN (1-481): 0: 901: 100.00
+	Hs
		1397421 PABP3_HUMAN (281-379): 5.42e-10: 63.9: 20.20		CI072_HUMAN (1-481): 0: 901: 100.00