Interactor 1: IST3 (P40565)
U2 snRNP component IST3 (Increased sodium tolerance protein 3) (U2 snRNP protein SNU17)
Gene: IST3

Interactor 2: CWC26 (P46947)
Pre-mRNA-splicing factor CWC26 (Bud site selection protein 13) (Complexed with CEF1 protein 26) (Synthetic lethal with CLF1 protein 7)
Gene: BUD13

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 10688190, 10655498, 11283351, 25218446, 11805837, 15565172, 16314500, 25160624, 18809678, 19033360, 37968396
Identification Methods two hybrid, two hybrid pooling approach, peptide array, isothermal titration calorimetry, nuclear magnetic resonance, anti tag coimmunoprecipitation, affinity chromatography technology, pull down, x-ray crystallography, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Bud13~RRM_1
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0005686 - U2 snRNP
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 148
Sc

1 266
+ Hs
+ At
+ Pf
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024