HitPredict

Interactor 1: MSL1 (P40567)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: MSL1

Interactor 2: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0071004 - U2-type prespliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 111 Sc			1 859
+	Hs
		1336499 PPIE_HUMAN (27-105): 2.02e-23: 93: 26.51		SYF1_HUMAN (30-845): 1.94e-154: 476: 21.48
+	Hs
		446799 SNRPA_HUMAN (2-106): 3.28e-12: 62.4: 18.52		SYF1_HUMAN (30-845): 1.94e-154: 476: 21.48
+	Hs
		1054602 RBM39_HUMAN (4-109): 9.05e-12: 61.7: 26.36		SYF1_HUMAN (30-845): 1.94e-154: 476: 21.48
+	Hs
		441376 RU2B_HUMAN (3-106): 2.3e-11: 59.7: 18.52		SYF1_HUMAN (30-845): 1.94e-154: 476: 21.48
+	Ce
		954283 Q9U2S6_CAEEL (27-105): 4.79e-11: 59.6: 28.92		P91175_CAEEL (19-840): 1.01e-154: 476: 20.96
+	Hs
		446637 SNRPA_HUMAN (2-106): 3.28e-12: 62.4: 18.52		SART3_HUMAN (398-838): 1.46e-44: 175: 13.31
+	Hs
		441287 RU2B_HUMAN (3-106): 2.3e-11: 59.7: 18.52		SART3_HUMAN (398-838): 1.46e-44: 175: 13.31
+	Hs
		300288 PPIE_HUMAN (27-105): 2.02e-23: 93: 26.51		PRP6_HUMAN (459-856): 1.36e-23: 109: 12.94
+	Sp
		1015540 RU2B_SCHPO (28-111): 1.1e-25: 94: 40.00		PRP1_SCHPO (202-841): 1.62e-17: 89.7: 8.50
+	Dm
		54167 PPIE_DROME (24-105): 3.93e-23: 92.3: 24.42		SYF1_DROME (67-572): 9.84e-18: 90.4: 9.65
+	Sc
		775731 MSL1_YEAST (1-111): 2.91e-31: 108: 100.00		CLF1_YEAST (4-377): 2.18e-12: 72.7: 11.71
+	Hs
		300036 SNRPA_HUMAN (2-106): 3.28e-12: 62.4: 18.52		PRP6_HUMAN (459-856): 1.36e-23: 109: 12.94
+	Hs
		300140 RBM39_HUMAN (4-109): 9.05e-12: 61.7: 26.36		PRP6_HUMAN (459-856): 1.36e-23: 109: 12.94
+	Hs
		300033 RU2B_HUMAN (3-106): 2.3e-11: 59.7: 18.52		PRP6_HUMAN (459-856): 1.36e-23: 109: 12.94
+	Hs
		1318165 PPIE_HUMAN (27-105): 2.02e-23: 93: 26.51		CRNL1_HUMAN (8-269): 3.6e-11: 69.3: 18.80
+	Hs
		446677 SNRPA_HUMAN (2-106): 3.28e-12: 62.4: 18.52		CTR9_HUMAN (302-847): 4.99e-12: 71.9: 9.92
+	Hs
		446782 SNRPA_HUMAN (2-106): 3.28e-12: 62.4: 18.52		CRNL1_HUMAN (8-269): 3.6e-11: 69.3: 18.80
+	Hs
		1054569 RBM39_HUMAN (4-109): 9.05e-12: 61.7: 26.36		CRNL1_HUMAN (8-269): 3.6e-11: 69.3: 18.80
+	Hs
		441365 RU2B_HUMAN (3-106): 2.3e-11: 59.7: 18.52		CRNL1_HUMAN (8-269): 3.6e-11: 69.3: 18.80
+	Hs
		230301 SNRPA_HUMAN (2-106): 3.28e-12: 62.4: 18.52		ZC3H1_HUMAN (229-807): 2.13e-09: 63.9: 10.93