Interactor 1: MLH1 (P40692)
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
Gene: MLH1
Interactor 2: MLH3 (Q9UHC1)
DNA mismatch repair protein Mlh3 (MutL protein homolog 3)
Gene: MLH3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.86 | 1.00 | 0.930 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11292842, 27229929, 32814343, 33961781, 24443562 |
| Identification Methods | two hybrid, biochemical, affinity chromatography technology, pull down, lexa vp16 complementation, two hybrid pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNA_mis_repair~HATPase_c_3, HATPase_c_3~HATPase_c_3, Mlh1_C~MutL_C |
| Common GO terms | GO:0000795 - synaptonemal complex GO:0001673 - male germ cell nucleus GO:0003682 - chromatin binding GO:0005524 - ATP binding GO:0005634 - nucleus and 5 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
