Interactor 1: MLH1 (P40692)
DNA mismatch repair protein Mlh1 (MutL protein homolog 1)
Gene: MLH1

Interactor 2: EXO1 (Q9UQ84)
Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI)
Gene: EXO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.755

The method score is based on:

Property Details
Experiments 11427529, 21533173, 14676842, 32814904, 19015241, 17148452, 22222486, 11429708, 12810663, 12414623
Identification Methods pull down, affinity chromatography technology, two hybrid, unspecified method, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006298 - mismatch repair
GO:0016446 - somatic hypermutation of immunoglobulin genes
and 1 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 756
Hs

1 846
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024