HitPredict

Interactor 1: RLP7 (P40693)
Ribosome biogenesis protein RLP7 (Ribosomal protein L7-like)
Gene: RLP7

Interactor 2: ERB1 (Q04660)
Ribosome biogenesis protein ERB1 (Eukaryotic ribosome biogenesis protein 1)
Gene: ERB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.747

Property	Details
Experiments	11805837, 11805826, 35615984, 23945946, 24129494, 16429126, 37968396
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 322 Sc			1 807
+	Hs
		1048859 RL7L_HUMAN (16-322): 1.79e-57: 187: 23.78		BOP1_HUMAN (64-806): 0: 567: 38.18
+	Dm
		1178814 Q9VKC1_DROME (13-320): 2.58e-62: 200: 28.39		BOP1_DROME (9-806): 1e-174: 524: 36.92
+	Sc
		630870 RLP7_YEAST (1-322): 4.14e-115: 337: 100.00		NLE1_YEAST (676-807): 3.44e-28: 121: 16.43
+	Hs
		574989 RL7_HUMAN (71-322): 4.22e-74: 230: 28.57		WDR5_HUMAN (330-665): 7.13e-47: 172: 11.53
+	Hs
		903298 RL7L_HUMAN (16-322): 1.79e-57: 187: 23.78		WDR5_HUMAN (330-665): 7.13e-47: 172: 11.53
+	Dm
		685607 RL7_DROME (34-321): 1.06e-71: 224: 26.64		LIS1_DROME (632-807): 4.47e-30: 125: 20.90
+	Hs
		575131 RL7_HUMAN (71-322): 4.22e-74: 230: 28.57		FBXW7_HUMAN (717-807): 4.36e-11: 68.6: 22.83