HitPredict

Interactor 1: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: TRI59 (Q8IWR1)
Tripartite motif-containing protein 59 (EC 2.3.2.27) (RING finger protein 104) (Tumor suppressor TSBF-1)
Gene: TRIM59

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.617

Property	Details
Experiments	34625908, 36523164, 29386185, 30902544
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 770 Hs			1 403
+	Hs
		776739 STAT3_HUMAN (1-770): 0: 1048: 100.00		TRI22_HUMAN (3-337): 9.41e-72: 234: 18.58
+	Hs
		776786 STAT3_HUMAN (1-770): 0: 1048: 100.00		TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55
+	Hs
		584894 STAT1_HUMAN (1-749): 0: 929: 51.52		RO52_HUMAN (1-352): 8.74e-78: 249: 16.15
+	Hs
		786411 STAT1_HUMAN (1-749): 0: 929: 51.52		TRI11_HUMAN (3-354): 8.45e-72: 234: 19.55
+	Mm
		1143658 Q8CFQ1_MOUSE (524-749): 2.28e-98: 306: 46.78		RO52_MOUSE (1-354): 1.51e-70: 230: 17.04