HitPredict

Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: SCRIB (Q7KRY7)
Protein lap4 (Protein scribble) (Protein smell-impaired)
Gene: SCRIB

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	27263975
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0007391 - dorsal closure GO:0007613 - memory
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 1851
+	Hs
		925273 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		1050061 RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		545370 RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		950989 RHOG_HUMAN (1-192): 2.98e-77: 230: 67.19		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		892367 RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		893999 CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		900463 RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79		SCRIB_HUMAN (1-1622): 6.71e-115: 404: 26.55
+	Hs
		925539 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Hs
		1301445 RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Hs
		545571 RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Hs
		951251 RHOG_HUMAN (1-192): 2.98e-77: 230: 67.19		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Hs
		892548 RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Hs
		894337 CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Hs
		900824 RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79		ERBIN_HUMAN (2-324): 3.77e-74: 275: 27.86
+	Hs
		925236 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		PTN13_HUMAN (562-1234): 4.69e-41: 169: 16.84
+	Hs
		1020215 RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32		PTN13_HUMAN (562-1234): 4.69e-41: 169: 16.84
+	Hs
		892339 RAC3_HUMAN (1-191): 1.08e-76: 229: 89.53		PTN13_HUMAN (562-1234): 4.69e-41: 169: 16.84
+	Hs
		893945 CDC42_HUMAN (1-192): 7.64e-77: 229: 69.27		PTN13_HUMAN (562-1234): 4.69e-41: 169: 16.84
+	Hs
		900421 RHOA_HUMAN (5-192): 1.44e-74: 224: 54.79		PTN13_HUMAN (562-1234): 4.69e-41: 169: 16.84
+	Hs
		564499 RHOQ_HUMAN (4-192): 9.76e-73: 220: 62.05		PTN13_HUMAN (562-1234): 4.69e-41: 169: 16.84