HitPredict

Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: Q8MSF1 (Q8MSF1)
GM23249p
Gene: Pura

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15710747
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0048812 - neuron projection morphogenesis GO:1904059 - regulation of locomotor rhythm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 369
+	Dm
		115195 RAC1_DROME (1-192): 3.66e-81: 240: 100.00		M9PEF7_DROME (1-369): 1.45e-96: 316: 100.00
+	Hs
		166482 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		MCF2L_HUMAN (1-296): 2.37e-77: 260: 23.64
+	Hs
		925727 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		PKHG1_HUMAN (2-362): 6.7e-63: 219: 16.02
+	Hs
		925461 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		ARH40_HUMAN (1-259): 7.88e-58: 204: 33.21
+	Hs
		925405 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		ARHGP_HUMAN (1-249): 1.02e-57: 198: 20.23
+	Hs
		500934 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		MCF2_HUMAN (3-219): 2.05e-55: 197: 18.67
+	Hs
		925330 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		PKHG4_HUMAN (1-201): 2.27e-55: 197: 45.77
+	Dm
		776888 RAC1_DROME (1-192): 3.66e-81: 240: 100.00		Q7K4E0_DROME (3-240): 5.87e-57: 202: 21.05
+	Ce
		975576 RAC1_CAEEL (1-192): 1.09e-81: 242: 80.73		Q7KPP4_CAEEL (8-273): 2.29e-53: 192: 19.56
+	Hs
		279854 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		TRIO_HUMAN (1-369): 7.64e-46: 170: 19.23
+	Hs
		224711 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		KALRN_HUMAN (1-356): 6.17e-39: 150: 17.76
+	Ce
		136793 RAC1_CAEEL (1-192): 1.09e-81: 242: 80.73		UNC89_CAEEL (4-189): 2.16e-37: 145: 17.37
+	Hs
		925622 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		PKHG2_HUMAN (2-341): 1.22e-34: 137: 13.17
+	Hs
		50580 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		PKHG3_HUMAN (2-352): 5.4e-33: 132: 16.06
+	Hs
		50617 RHOJ_HUMAN (2-190): 4.27e-80: 239: 60.32		PKHG3_HUMAN (2-352): 5.4e-33: 132: 16.06
+	Hs
		50554 RAC2_HUMAN (1-192): 5.01e-80: 238: 89.06		PKHG3_HUMAN (2-352): 5.4e-33: 132: 16.06
+	Dm
		776891 RAC1_DROME (1-192): 3.66e-81: 240: 100.00		Q7YZA0_DROME (1-123): 2.29e-31: 127: 24.19
+	Dm
		71592 RAC1_DROME (1-192): 3.66e-81: 240: 100.00		B3DN64_DROME (2-321): 1.18e-12: 71.3: 10.23
+	Hs
		925320 RAC1_HUMAN (1-192): 2.19e-83: 246: 91.67		PKHG6_HUMAN (16-369): 1.6e-10: 64.7: 11.39
+	Dm
		776895 RAC1_DROME (1-192): 3.66e-81: 240: 100.00		Q8MSP7_DROME (2-321): 2.71e-12: 70.5: 10.23