Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: PAK (Q9VI13)
Serine/threonine-protein kinase Pak (EC 2.7.11.1)
Gene: PAK

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 14527437, 14555990, 8628256, 11604137, 17011730, 10847683, 15710747, unassigned4
Identification Methods affinity chromatography technology, two hybrid, two hybrid fragment pooling approach, pull down, experimental interaction detection
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains PBD~Ras, Pkinase~Ras
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0007391 - dorsal closure
GO:0007395 - dorsal closure, spreading of leading edge cells
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 192
Dm

1 704
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+ Dd
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+ Ce
+ Mm
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+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024